Persistent insulin signaling coupled with restricted PI3K activation causes insulin-induced vasoconstriction

Insulin modulates vasomotor tone through vasodilator and vasoconstrictor signaling pathways. The purpose of the present work was to determine whether insulin-stimulated vasoconstriction is a pathophysiological phenomenon that can result from a combination of persistent insulin signaling, suppressed...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Olver, T. Dylan, Grunewald, Zachary I., Ghiarone, Thaysa, Restaino, Robert M., Sales, Allan R. K., Park, Lauren K., Thorne, Pamela K., Ganga, Rama Rao, Emter, Craig A., Lemon, Peter W. R., Shoemaker, J. Kevin, Manrique-Acevedo, Camila, Martinez-Lemus, Luis A., Padilla, Jaume
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879917/
https://ncbi.nlm.nih.gov/pubmed/31603345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00464.2019
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