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Integrating multiomics longitudinal data to reconstruct networks underlying lung development

A comprehensive understanding of the dynamic regulatory networks that govern postnatal alveolar lung development is still lacking. To construct such a model, we profiled mRNA, microRNA, DNA methylation, and proteomics of developing murine alveoli isolated by laser capture microdissection at 14 prede...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Ding, Jun, Ahangari, Farida, Espinoza, Celia R., Chhabra, Divya, Nicola, Teodora, Yan, Xiting, Lal, Charitharth V., Hagood, James S., Kaminski, Naftali, Bar-Joseph, Ziv, Ambalavanan, Namasivayam
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879899/
https://ncbi.nlm.nih.gov/pubmed/31432713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00554.2018
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