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Knockout of the neonatal Fc receptor in cultured podocytes alters IL-6 signaling and the actin cytoskeleton

The neonatal Fc receptor (FcRn) has been shown to be required for antigen presentation in dendritic cells, and global knockout of FcRn attenuates immune-mediated kidney disease. Podocytes express interleukin-6 (IL-6) receptor and produce IL-6 under proinflammatory conditions. Here we examined the ro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Cell Physiol
Egile Nagusiak: Tonsawan, Pantipa, Dylewski, James, Lewis, Linda, Blaine, Judith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879880/
https://ncbi.nlm.nih.gov/pubmed/31553647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00235.2019
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