Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity

Posttraumatic stress disorder (PTSD) is associated with neuroendocrine alterations and metabolic abnormalities; however, how metabolism is affected by neuroendocrine disturbances is unclear. The data from combat-exposed veterans with PTSD show increased glycolysis to lactate flux, reduced TCA cycle...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Somvanshi, Pramod R., Mellon, Synthia H., Flory, Janine D., Abu-Amara, Duna, Wolkowitz, Owen M., Yehuda, Rachel, Jett, Marti, Hood, Leroy, Marmar, Charles, Doyle, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879860/
https://ncbi.nlm.nih.gov/pubmed/31322414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00065.2019
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