Skeletal myofiber VEGF deficiency leads to mitochondrial, structural, and contractile alterations in mouse diaphragm

Diaphragm dysfunction accompanies cardiopulmonary disease and impaired oxygen delivery. Vascular endothelial growth factor (VEGF) regulates oxygen delivery through angiogenesis, capillary maintenance, and contraction-induced perfusion. We hypothesized that myofiber-specific VEGF deficiency contribut...

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Vydáno v:J Appl Physiol (1985)
Hlavní autoři: Cannon, Daniel T., Rodewohl, Lukas, Adams, Volker, Breen, Ellen C., Bowen, T. Scott
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879833/
https://ncbi.nlm.nih.gov/pubmed/31487223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00779.2018
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