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Feature article: LCZ696, an angiotensin receptor-neprilysin inhibitor, ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis

Diabetic cardiomyopathy, which refers to the destruction of the structure and function of the heart, is the primary cause of heart failure due to diabetes. LCZ696 is the first angiotensin receptor-neprilysin inhibitor (ARNi) to be used clinically. Our study investigated the role played by LCZ696 dur...

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Détails bibliographiques
Publié dans:Exp Biol Med (Maywood)
Auteurs principaux: Ge, Qing, Zhao, Li, Ren, Xiao-Min, Ye, Peng, Hu, Zuo-Ying
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879777/
https://ncbi.nlm.nih.gov/pubmed/31262190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219861283
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