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Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network
The disproportionately high prevalence of male cancer is poorly understood. We tested for sex-disparity in the functional integrity of the major tumor suppressor p53 in sporadic cancers. Our bioinformatics analyses expose three novel levels of p53 impact on sex-disparity in 12 non-reproductive cance...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6879765/ https://ncbi.nlm.nih.gov/pubmed/31772231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13266-3 |
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