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The Actin-Capping Protein Alpha-Adducin Is Required for T-Cell Costimulation

Alpha-adducin (Add1) is a critical component of the actin-spectrin network in erythrocytes, acting to cap the fast-growing, barbed ends of actin filaments, and recruiting spectrin to these junctions. Add1 is highly expressed in T cells, but its role in T-cell activation has not been examined. Using...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Thauland, Timothy J., Khan, Humza A., Butte, Manish J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879651/
https://ncbi.nlm.nih.gov/pubmed/31824498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02706
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