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Identification and characterization of a novel sesquiterpene synthase, 4-amorphen-11-ol synthase, from Artemisia maritima

Artemisinin, a sesquiterpene lactone exhibiting effective antimalarial activity, is produced by only Artemisia annua plant. A key step in artemisinin biosynthesis is the cyclization of farnesyl pyrophosphate (FPP) to amorpha-4,11-diene catalyzed by amorpha-4,11-diene synthase (AaADS). Intriguingly,...

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Detalhes bibliográficos
Publicado no:Plant Biotechnol (Tokyo)
Main Authors: Muangphrom, Paskorn, Seki, Hikaru, Matsumoto, Seiya, Nishiwaki, Mika, Fukushima, Ery O., Muranaka, Toshiya
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society for Plant Cell and Molecular Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879386/
https://ncbi.nlm.nih.gov/pubmed/31819713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5511/plantbiotechnology.18.0324a
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