Neto proteins regulate gating of the kainate-type glutamate receptor GluK2 through two binding sites

The neuropilin and tolloid-like (Neto) proteins Neto1 and Neto2 are auxiliary subunits of kainate-type glutamate receptors (KARs) that regulate KAR trafficking and gating. However, how Netos bind and regulate the biophysical functions of KARs remains unclear. Here, we found that the N-terminal domai...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Li, Yan-Jun, Duan, Gui-Fang, Sun, Jia-Hui, Wu, Dan, Ye, Chang, Zang, Yan-Yu, Chen, Gui-Quan, Shi, Yong-Yun, Wang, Jun, Zhang, Wei, Shi, Yun Stone
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879349/
https://ncbi.nlm.nih.gov/pubmed/31628192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008631
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