No Evidence of Plasmodium falciparum k13 Artemisinin Resistance-Conferring Mutations over a 24-Year Analysis in Coastal Kenya but a Near Complete Reversion to Chloroquine-Sensitive Parasites

Antimalarial drug resistance is a substantial impediment to malaria control. The spread of resistance has been described using genetic markers, which are important epidemiological tools. We carried out a temporal analysis of changes in allele frequencies of 12 drug resistance markers over 2 decades...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wamae, Kevin, Okanda, Dorcas, Ndwiga, Leonard, Osoti, Victor, Kimenyi, Kelvin M., Abdi, Abdirahman I., Bejon, Philip, Sutherland, Colin, Ochola-Oyier, Lynette Isabella
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Epidemiology and Surveillance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879256/
https://ncbi.nlm.nih.gov/pubmed/31591113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01067-19
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