Derepression of the smvA Efflux System Arises in Clinical Isolates of Proteus mirabilis and Reduces Susceptibility to Chlorhexidine and Other Biocides

Proteus mirabilis is a common pathogen of the catheterized urinary tract and often described as intrinsically resistant to the biocide chlorhexidine (CHD). Here, we demonstrate that derepression of the smvA efflux system has occurred in clinical isolates of P. mirabilis and reduces susceptibility to...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Pelling, H., Bock, L. J., Nzakizwanayo, J., Wand, M. E., Denham, E. L., MacFarlane, W. M., Sutton, J. M., Jones, B. V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879213/
https://ncbi.nlm.nih.gov/pubmed/31570392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01535-19
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