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Towards Early Monitoring of Chemotherapy-induced Drug Resistance Based on Single Cell Metabolomics: Combining Single-probe Mass Spectrometry with Machine Learning

Despite the presence of methods evaluating drug resistance during chemotherapies, techniques, which allow for monitoring the degree of drug resistance in early chemotherapeutic stage from single cells in their native microenvironment, are still absent. Herein, we report an analytical approach that c...

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Detalhes bibliográficos
Publicado no:Anal Chim Acta
Main Authors: Liu, Renmeng, Sun, Mei, Zhang, Genwei, Lan, Yunpeng, Yang, Zhibo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878984/
https://ncbi.nlm.nih.gov/pubmed/31708031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2019.09.065
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