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Macrophage transcriptome modification induced by hypoxia and lactate

The production of lactate under hypoxic conditions or by cancer cells was reported to promote the M2 polarization of tumor-associated macrophages. However, the exact effect of lactate on macrophages, particularly under hypoxic conditions, has remained largely elusive. In the present study, an in-dep...

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Bibliografski detalji
Izdano u:Exp Ther Med
Glavni autori: Zhao, Yang, Zhao, Bin, Wang, Xin, Guan, Ge, Xin, Yang, Sun, Yan Dong, Wang, Jian Hong, Guo, Yuan, Zang, Yun Jin
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878900/
https://ncbi.nlm.nih.gov/pubmed/31798707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.8164
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