Mucoadhesive Particles: A Novel, Prolonged-Release Nanocarrier of Sitagliptin for the Treatment of Diabetics

Sitagliptin (MK–0431) is a widely and commonly used oral hypoglycemic drug in the treatment of type 2 diabetes mellitus; patients typically take higher doses of this drug (50 mg, twice daily). One drawback is that only 38% of the drug is bound reversibly to plasma proteins and 79% is excreted in uri...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: SreeHarsha, Nagaraja, Ramnarayanan, Chandramouli, Al-Dhubiab, Bandar E., Nair, Anroop B., Hiremath, Jagadeesh G., Venugopala, Katharigatta N., Satish, Roopashree T., Attimarad, Mahesh, Shariff, Arshia
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878770/
https://ncbi.nlm.nih.gov/pubmed/31815135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3950942
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