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Blinding in clozapine trials: a problem and a potential solution

Background: A methodological problem arises when efficacy of clozapine is compared with other antipsychotic medication in double blind randomized studies. Due to the risk of leucopenia and agranulocytosis, patients in the clozapine condition need to have regular blood testing. The problem is that in...

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Bibliographic Details
Published in:Int J Methods Psychiatr Res
Main Authors: Wohlfarth, Tamar, Linszen, Don, Van Den Brink, Wim
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd. 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878280/
https://ncbi.nlm.nih.gov/pubmed/19701925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mpr.291
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