Genetically Modified Porcine Mesenchymal Stem Cells by Lentiviral Tbx18 Create a Biological Pacemaker

BACKGROUND: Tbx18 is a vital transcription factor involved in embryonic sinoatrial node (SAN) formation process but is gradually vanished after birth. Myocardial injection of lentiviral Tbx18 converts cardiomyocytes into pacemaker-like cells morphologically and functionally. In this in vitro and in...

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Bibliografski detalji
Izdano u:Stem Cells Int
Glavni autori: Hu, Yannan, Li, Ning, Liu, Liang, Zhang, Hao, Xue, Xiang, Shao, Xin, Zhang, Yu, Lang, Xilong
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877911/
https://ncbi.nlm.nih.gov/pubmed/31814832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3621314
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