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Sex differences in the hypothalamic–pituitary–adrenal axis: An obstacle to antidepressant drug development?

Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has long been implicated in the pathophysiology of depression, and HPA axis‐based compounds have served as potential new therapeutic targets, but with no success. This review details sex differences from animal and human studies in the function o...

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Publicado en:Br J Pharmacol
Main Authors: Kokras, Nikolaos, Hodes, Georgia E., Bangasser, Debra A., Dalla, Christina
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877794/
https://ncbi.nlm.nih.gov/pubmed/31093959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14710
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