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Sex differences in the hypothalamic–pituitary–adrenal axis: An obstacle to antidepressant drug development?

Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has long been implicated in the pathophysiology of depression, and HPA axis‐based compounds have served as potential new therapeutic targets, but with no success. This review details sex differences from animal and human studies in the function o...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Kokras, Nikolaos, Hodes, Georgia E., Bangasser, Debra A., Dalla, Christina
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877794/
https://ncbi.nlm.nih.gov/pubmed/31093959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14710
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