Cell Mass Increase Associated with Formation of Glucose‐Controlling β‐Cell Mass in Device‐Encapsulated Implants of hiPS‐Derived Pancreatic Endoderm

Device‐encapsulated human stem cell‐derived pancreatic endoderm (PE) can generate functional β‐cell implants in the subcutis of mice, which has led to the start of clinical studies in type 1 diabetes. Assessment of the formed functional β‐cell mass (FBM) and its correlation with in vivo metabolic ma...

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Pubblicato in:Stem Cells Transl Med
Autori principali: Robert, Thomas, De Mesmaeker, Ines, Van Hulle, Freya O., Suenens, Krista G., Stangé, Geert M., Ling, Zhidong, Haller, Corinne, Bouche, Nicolas, Keymeulen, Bart, Kraus, Marine R.C., Pipeleers, Daniel G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
Soggetti:
Tissue Engineering and Regenerative Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877770/
https://ncbi.nlm.nih.gov/pubmed/31379140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.19-0043
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