Naringenin Ameliorates Drosophila ReepA Hereditary Spastic Paraplegia-Linked Phenotypes

Defects in the endoplasmic reticulum (ER) membrane shaping and interaction with other organelles seem to be a crucial mechanism underlying Hereditary Spastic Paraplegia (HSP) neurodegeneration. REEP1, a transmembrane protein belonging to TB2/HVA22 family, is implicated in SPG31, an autosomal dominan...

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Detalles Bibliográficos
Publicado en:Front Neurosci
Autores principales: Napoli, Barbara, Gumeni, Sentiljana, Forgiarini, Alessia, Fantin, Marianna, De Filippis, Concetta, Panzeri, Elena, Vantaggiato, Chiara, Orso, Genny
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877660/
https://ncbi.nlm.nih.gov/pubmed/31803000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01202
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