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Proton Pump Inhibitors Modulate Transport Of Doxorubicin And Its Liposomal Form Into 2D And 3D Breast Cancer Cell Cultures

PURPOSE: The purpose of our study was to evaluate the influence of two PPIs (omeprazole (OME) and lansoprazole (LANSO)) on weakly basic anticancer drug doxorubicin (DOX) and pegylated liposomal doxorubicin (PLD) delivery to monolayer-cultured 4T1 murine breast cancer cells and tumor spheroids. METHO...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Manag Res
Main Authors: Paškevičiūtė, Miglė, Petrikaitė, Vilma
Format: Artigo
Jezik:Inglês
Izdano: Dove 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877465/
https://ncbi.nlm.nih.gov/pubmed/31819614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S224097
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