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Apolipoprotein M-bound sphingosine-1-phosphate regulates blood–brain barrier paracellular permeability and transcytosis

The blood-brain barrier (BBB) is formed by the endothelial cells lining cerebral microvessels, but how blood-borne signaling molecules influence permeability is incompletely understood. We here examined how the apolipoprotein M (apoM)-bound sphingosine 1–phosphate (S1P) signaling pathway affects the...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mathiesen Janiurek, Mette, Soylu-Kucharz, Rana, Christoffersen, Christina, Kucharz, Krzysztof, Lauritzen, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877292/
https://ncbi.nlm.nih.gov/pubmed/31763978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49405
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