Power behind the throne: A clinical trial simulation study evaluating the impact of controllable design factors on the power of antidepressant trials

OBJECTIVE: To evaluate the impact of controllable design factors on the power of antidepressants trials. METHODS: Using clinical trial simulation (CTS), we analyzed the combined impact on the power of trials of controllable design factors (sample size, outcome metrics, and disease severity at inclus...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Methods Psychiatr Res
Main Authors: Chevance, Astrid, Naudet, Florian, Gaillard, Raphaël, Ravaud, Philippe, Porcher, Raphaël
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877224/
https://ncbi.nlm.nih.gov/pubmed/30997716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mpr.1779
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