Upregulation of ERK phosphorylation in rat dorsal root ganglion neurons contributes to oxaliplatin-induced chronic neuropathic pain

Oxaliplatin is the first-line chemotherapy for metastatic colorectal cancer. Unlike other platinum anticancer agents, oxaliplatin does not result in significant renal impairment and ototoxicity. Oxaliplatin, however, has been associated with acute and chronic peripheral neuropathies. Despite the awa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Maruta, Toyoaki, Nemoto, Takayuki, Hidaka, Koutaro, Koshida, Tomohiro, Shirasaka, Tetsuro, Yanagita, Toshihiko, Takeya, Ryu, Tsuneyoshi, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876879/
https://ncbi.nlm.nih.gov/pubmed/31765435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225586
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