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Optogenetic gamma stimulation rescues memory impairments in an Alzheimer’s disease mouse model
Slow gamma oscillations (30–60 Hz) correlate with retrieval of spatial memory. Altered slow gamma oscillations have been observed in Alzheimer’s disease. Here, we use the J20-APP AD mouse model that displays spatial memory loss as well as reduced slow gamma amplitude and phase-amplitude coupling to...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6876640/ https://ncbi.nlm.nih.gov/pubmed/31757962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13260-9 |
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