Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

Macrophages are strongly adapted to their tissue of residence. Yet, little is known about the cell-cell interactions that imprint the tissue-specific identities of macrophages in their respective niches. Using conditional depletion of liver Kupffer cells, we traced the developmental stages of monocy...

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Publié dans:Immunity
Auteurs principaux: Bonnardel, Johnny, T’Jonck, Wouter, Gaublomme, Djoere, Browaeys, Robin, Scott, Charlotte L., Martens, Liesbet, Vanneste, Bavo, De Prijck, Sofie, Nedospasov, Sergei A., Kremer, Anna, Van Hamme, Evelien, Borghgraef, Peter, Toussaint, Wendy, De Bleser, Pieter, Mannaerts, Inge, Beschin, Alain, van Grunsven, Leo A., Lambrecht, Bart N., Taghon, Tom, Lippens, Saskia, Elewaut, Dirk, Saeys, Yvan, Guilliams, Martin
Format: Artigo
Langue:Inglês
Publié: Cell Press 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876284/
https://ncbi.nlm.nih.gov/pubmed/31561945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.08.017
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