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The new entries in the therapeutic armamentarium: The small molecule JAK inhibitors

The past decade has witnessed an explosion in trial data on JAK inhibitors (JAKi). These small molecules target the Janus kinase - signal transducer and activator of transcription (JAK-STAT) pathway, blocking crucial cytokines across a septum of rheumatic diseases. As a class, JAKi are beginning to...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Bechman, Katie, Yates, Mark, Galloway, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876279/
https://ncbi.nlm.nih.gov/pubmed/31401212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2019.104392
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