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Resilience of T cell-intrinsic dysfunction in transplantation tolerance

Following antigen stimulation, naïve T cells differentiate into memory cells that mediate antigen clearance more efficiently upon repeat encounter. Donor-specific tolerance can be achieved in a subset of transplant recipients, but some of these grafts are rejected after years of stability, often fol...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Miller, Michelle L., McIntosh, Christine M., Wang, Ying, Chen, Luqiu, Wang, Peter, Lei, Yuk Man, Daniels, Melvin D., Watkins, Elyse, Mora Solano, Carolina, Chong, Anita S., Alegre, Maria-Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876241/
https://ncbi.nlm.nih.gov/pubmed/31685610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910298116
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