PIEZO2 mediates injury-induced tactile pain in mice and humans

Tissue injury and inflammation markedly alter touch perception, making normally innocuous sensations become intensely painful. Although this sensory distortion, known as tactile allodynia, is one of the most common types of pain, the mechanism by which gentle mechanical stimulation becomes unpleasan...

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Pubblicato in:Sci Transl Med
Autori principali: Szczot, Marcin, Liljencrantz, Jaquette, Ghitani, Nima, Barik, Arnab, Lam, Ruby, Thompson, James H., Bharucha-Goebel, Diana, Saade, Dimah, Necaise, Aaron, Donkervoort, Sandra, Foley, A. Reghan, Gordon, Taylor, Case, Laura, Bushnell, M. Catherine, Bönnemann, Carsten G., Chesler, Alexander T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875774/
https://ncbi.nlm.nih.gov/pubmed/30305456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat9892
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