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Intrathecal IgG Synthesis and Persistent Inflammation Are Associated with White Matter Lesions in HIV-negative Patients with Cryptococcal Meningoencephalitis

OBJECTIVE: Cryptococcal meningoencephalitis (CM) causes significant morbidity and mortality in human immunodeficiency virus (HIV)-negative and HIV-positive populations. White matter lesions (WMLs) have been reported in both populations of CM patients; however, the mechanisms underlying WML formation...

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Detalhes bibliográficos
Publicado no:Intern Med
Main Authors: Ohyagi, Masaki, Irioka, Takashi, Ohkubo, Takuya, Ishibashi, Satoru, Takahashi, Yuko K, Amano, Eiichiro, Machida, Akira, Kuwahara, Hiroya, Yokota, Takanori
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Internal Medicine 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875458/
https://ncbi.nlm.nih.gov/pubmed/31243232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.2338-18
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