miR-23b Negatively Regulates Sepsis-Induced Inflammatory Responses by Targeting ADAM10 in Human THP-1 Monocytes

BACKGROUND: Previous studies have demonstrated pivotal roles of disintegrin and metalloproteinase 10 (ADAM10) in the pathogenesis of sepsis. MicroRNA- (miR-) 23b has emerged as an anti-inflammatory factor that prevents multiple autoimmune diseases. However, the underlying mechanisms of miR-23b in th...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Zhang, Wenying, Lu, Furong, Xie, Yuliu, Lin, Yao, Zhao, Tian, Tao, Shoubao, Lai, Zhipeng, Wei, Ning, Yang, Ruoxuan, Shao, Yiming, He, Junbing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875296/
https://ncbi.nlm.nih.gov/pubmed/31780861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5306541
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