Metformin Activates the Protective Effects of the AMPK Pathway in Acute Lung Injury Caused by Paraquat Poisoning

OBJECTIVE: To observe whether metformin (MET) plays a protective role in acute lung injury (ALI) induced by paraquat (PQ) poisoning in rats by activating the AMPK/NF-κB signaling pathway. METHODS: PQ exposure was used to construct a rat model of ALI and a model of acute type II alveolar epithelial c...

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Publicat a:Oxid Med Cell Longev
Autors principals: Wu, Liaozhang, Cen, Yifang, Feng, Menglong, Zhou, Yanna, Tang, Hui, Liao, Xueli, Wang, Yanze, Wang, Min, Zhou, Manhong
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875205/
https://ncbi.nlm.nih.gov/pubmed/31781324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1709718
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