Lyophilized B. subtilis ZB183 Spores: 90-Day Repeat Dose Oral (Gavage) Toxicity Study in Wistar Rats

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on lyophilized spores of the novel genetically modified strain B. subtilis ZB183. Lyophilized spores at doses of 10(9), 10(10), and 10(11) CFU/kg body weight/day were administered by oral gavage t...

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發表在:J Toxicol
Main Authors: Appala Naidu, B., Kannan, Kamala, Santhosh Kumar, D. P., Oliver, John W. K., Abbott, Zachary D.
格式: Artigo
語言:Inglês
出版: Hindawi 2019
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875028/
https://ncbi.nlm.nih.gov/pubmed/31781202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3042108
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