The 5-Lipoxygenase Inhibitor Zileuton Protects Pressure Overload-Induced Cardiac Remodeling via Activating PPARα

Zileuton has been demonstrated to be an anti-inflammatory agent due to its well-known ability to inhibit 5-lipoxygenase (5-LOX). However, the effects of zileuton on cardiac remodeling are unclear. In this study, the effects of zileuton on pressure overload-induced cardiac remodeling were investigate...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wu, Qing-Qing, Deng, Wei, Xiao, Yang, Chen, Jiao-Jiao, Liu, Chen, Wang, Juan, Guo, Yankai, Duan, Mingxia, Cai, Zhulan, Xie, Saiyang, Yuan, Yuan, Tang, Qizhu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874937/
https://ncbi.nlm.nih.gov/pubmed/31781348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7536803
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