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White matter has impaired resting oxygen delivery in sickle cell patients

Although modern medical management has lowered overt stroke occurrence in patients with sickle cell disease (SCD), progressive white matter (WM) damage remains common. It is known that cerebral blood flow (CBF) increases to compensate for anemia, but sufficiency of cerebral oxygen delivery, especial...

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Bibliografski detalji
Izdano u:Am J Hematol
Glavni autori: Chai, Yaqiong, Bush, Adam M., Coloigner, Julie, Nederveen, Aart J., Tamrazi, Benita, Vu, Chau, Choi, Soyoung, Coates, Thomas D., Lepore, Natasha, Wood, John C.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874897/
https://ncbi.nlm.nih.gov/pubmed/30697803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25423
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