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White matter has impaired resting oxygen delivery in sickle cell patients

Although modern medical management has lowered overt stroke occurrence in patients with sickle cell disease (SCD), progressive white matter (WM) damage remains common. It is known that cerebral blood flow (CBF) increases to compensate for anemia, but sufficiency of cerebral oxygen delivery, especial...

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Détails bibliographiques
Publié dans:Am J Hematol
Auteurs principaux: Chai, Yaqiong, Bush, Adam M., Coloigner, Julie, Nederveen, Aart J., Tamrazi, Benita, Vu, Chau, Choi, Soyoung, Coates, Thomas D., Lepore, Natasha, Wood, John C.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874897/
https://ncbi.nlm.nih.gov/pubmed/30697803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25423
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