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White matter has impaired resting oxygen delivery in sickle cell patients

Although modern medical management has lowered overt stroke occurrence in patients with sickle cell disease (SCD), progressive white matter (WM) damage remains common. It is known that cerebral blood flow (CBF) increases to compensate for anemia, but sufficiency of cerebral oxygen delivery, especial...

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Detalhes bibliográficos
Publicado no:Am J Hematol
Main Authors: Chai, Yaqiong, Bush, Adam M., Coloigner, Julie, Nederveen, Aart J., Tamrazi, Benita, Vu, Chau, Choi, Soyoung, Coates, Thomas D., Lepore, Natasha, Wood, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874897/
https://ncbi.nlm.nih.gov/pubmed/30697803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25423
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