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Targeting Frizzled-7 Decreases Stemness and Chemotherapeutic Resistance in Gastric Cancer Cells by Suppressing Myc Expression

BACKGROUND: Although the promoting roles of Frizzled-7 (Fzd7) have been shown before, its effects in gastric cancer (GC) cell stemness are still unclear. The present study assessed the effects of Fzd7 on GC cell stemness and chemoresistance. MATERIAL/METHODS: Clinical samples were used to detect Fzd...

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Publicat a:Med Sci Monit
Autors principals: Cheng, Yongzhong, Li, Li, Pan, Sirong, Jiang, Huilin, Jin, Hongyan
Format: Artigo
Idioma:Inglês
Publicat: International Scientific Literature, Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874837/
https://ncbi.nlm.nih.gov/pubmed/31733054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.918504
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