High-throughput single cell sequencing with linear amplification

Conventional methods for single cell genome sequencing are limited with respect to uniformity and throughput. Here we describe ‘sci-L3’, a single cell sequencing method that combines combinatorial indexing (‘sci-’) and linear (‘L’) amplification. The sci-L3 method adopts a 3-level (‘3’) indexing sch...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Yin, Yi, Jiang, Yue, Lam, Kwan-Wood Gabriel, Berletch, Joel B., Disteche, Christine M., Noble, William S., Steemers, Frank J., Camerini-Otero, R. Daniel, Adey, Andrew C., Shendure, Jay
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874760/
https://ncbi.nlm.nih.gov/pubmed/31495564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.08.002
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