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Family-wide annotation of enzymatic pathways by parallel in vivo metabolomics
Enzymes catalyze fundamental biochemical reactions that control cellular and organismal homeostasis. Here we present an approach for de novo biochemical pathway discovery across entire enzyme families using parallel viral transduction in mice and untargeted liquid chromatography-mass spectrometry. A...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6874721/ https://ncbi.nlm.nih.gov/pubmed/31587987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.09.009 |
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