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Defective Proliferation and Osteogenic Potential with Altered Immunoregulatory phenotype of Native Bone marrow-Multipotential Stromal Cells in Atrophic Fracture Non-Union

Bone marrow-Multipotential stromal cells (BM-MSCs) are increasingly used to treat complicated fracture healing e.g., non-union. Though, the quality of these autologous cells is not well characterized. We aimed to evaluate bone healing-related capacities of non-union BM-MSCs. Iliac crest-BM was aspir...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: El-Jawhari, Jehan J., Kleftouris, George, El-Sherbiny, Yasser, Saleeb, Hany, West, Robert M., Jones, Elena, Giannoudis, Peter V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874596/
https://ncbi.nlm.nih.gov/pubmed/31758052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53927-3
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