Pleiotropic effects of alpha-SNAP M105I mutation on oocyte biology: ultrastructural and cellular changes that adversely affect female fertility in mice

After sperm-oocyte fusion, cortical granules (CGs) located in oocyte cortex undergo exocytosis and their content is released into the perivitelline space to avoid polyspermy. Thus, cortical granule exocytosis (CGE) is a key process for fertilization success. We have demonstrated that alpha-SNAP -and...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: de Paola, Matilde, Miró, María Paz, Ratto, Marcelo, Bátiz, Luis Federico, Michaut, Marcela Alejandra
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874563/
https://ncbi.nlm.nih.gov/pubmed/31758001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53574-8
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