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An isogenic hiPSC-derived BBB-on-a-chip

The blood-brain barrier (BBB) is composed of brain microvascular endothelial cells (BMECs) that regulate brain homeostasis, and astrocytes within the brain are involved in the maintenance of the BBB or modulation of its integrity in disease states via secreted factors. A major challenge in modeling...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomicrofluidics
Hauptverfasser: Motallebnejad, Pedram, Thomas, Andrew, Swisher, Sarah L., Azarin, Samira M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: AIP Publishing LLC 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874510/
https://ncbi.nlm.nih.gov/pubmed/31768205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5123476
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