Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

This study explored the influence of long non-coding RNA (lncRNA) SNHG14 on α-synuclein (α-syn) expression and Parkinson’s disease (PD) pathogenesis. Firstly, we found that the expression level of SNHG14 was elevated in brain tissues of PD mice. In MN9D cells, the rotenone treatment (1μmol/L) enhanc...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Zhang, Li-Min, Wang, Meng-Han, Yang, He-Cheng, Tian, Tian, Sun, Gui-Fang, Ji, Yang-Fei, Hu, Wen-Tao, Liu, Xi, Wang, Jian-Ping, Lu, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874444/
https://ncbi.nlm.nih.gov/pubmed/31683259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102330
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