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TGF-β- and lipopolysaccharide-induced upregulation of circular RNA PWWP2A promotes hepatic fibrosis via sponging miR-203 and miR-223

Both transforming growth factor-beta (TGF-β) and lipopolysaccharide (LPS) can activate hepatic stellate cells (HSCs), thus increasing expressions of alpha smooth muscle actin (α-SMA) and type I collagen alpha 1 (Col1α1) and promoting liver fibrosis. However, whether TGF-β and LPS have a common downs...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Autores principales: Liu, Wentao, Feng, Ruo, Li, Xingxing, Li, Dingyang, Zhai, Wenlong
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874441/
https://ncbi.nlm.nih.gov/pubmed/31719209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102405
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