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Surveillance to maintain the sensitivity of genotype-based antibiotic resistance diagnostics

The sensitivity of genotype-based diagnostics that predict antimicrobial susceptibility is limited by the extent to which they detect genes and alleles that lead to resistance. As novel resistance variants are expected to emerge, such sensitivity is expected to decline unless the new variants are de...

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Detalles Bibliográficos
Publicado en:PLoS Biol
Main Authors: Hicks, Allison L., Kissler, Stephen M., Lipsitch, Marc, Grad, Yonatan H.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874359/
https://ncbi.nlm.nih.gov/pubmed/31714937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000547
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