The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer

Notwithstanding the positive clinical impact of endocrine therapies in estrogen receptor-alpha (ERα)-positive breast cancer, de novo and acquired resistance limits the therapeutic lifespan of existing drugs. Taking the position that resistance is nearly inevitable, we undertook a study to identify a...

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Publicado no:Cell Rep
Main Authors: Cocce, Kimberly J., Jasper, Jeff S., Desautels, Taylor K., Everett, Logan, Wardell, Suzanne, Westerling, Thomas, Baldi, Robert, Wright, Tricia M., Tavares, Kendall, Yllanes, Alex, Bae, Yeeun, Blitzer, Jeremy T., Logsdon, Craig, Rakiec, Daniel P., Ruddy, David A., Jiang, Tiancong, Broadwater, Gloria, Hyslop, Terry, Hall, Allison, Laine, Muriel, Phung, Linda, Greene, Geoffrey L., Martin, Lesley-Ann, Pancholi, Sunil, Dowsett, Mitch, Detre, Simone, Marks, Jeffrey R., Crawford, Gregory E., Brown, Myles, Norris, John D., Chang, Ching-yi, McDonnell, Donald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874102/
https://ncbi.nlm.nih.gov/pubmed/31644911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.09.032
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