SS-31 Peptide Reverses the Mitochondrial Fragmentation Present in Fibroblasts From Patients With DCMA, a Mitochondrial Cardiomyopathy

We used patient dermal fibroblasts to characterize the mitochondrial abnormalities associated with the dilated cardiomyopathy with ataxia syndrome (DCMA) and to study the effect of the mitochondrially-targeted peptide SS-31 as a potential novel therapeutic. DCMA is a rare and understudied autosomal...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Cardiovasc Med
Egile Nagusiak: Machiraju, Pranav, Wang, Xuemei, Sabouny, Rasha, Huang, Joshua, Zhao, Tian, Iqbal, Fatima, King, Melissa, Prasher, Dimple, Lodha, Arijit, Jimenez-Tellez, Nerea, Ravandi, Amir, Argiropoulos, Bob, Sinasac, David, Khan, Aneal, Shutt, Timothy E., Greenway, Steven C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Cardiovascular Medicine
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873783/
https://ncbi.nlm.nih.gov/pubmed/31803760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2019.00167
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