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Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission

BACKGROUND: Vaccine escape mutants (VEMs) are one of the causes of breakthrough infections in the mother-to-child transmission of hepatitis B virus (HBV). We hypothesized that VEMs existing as minor populations in the maternal blood are associated with breakthrough infections in children. We sought...

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Bibliographic Details
Published in:BMC Infect Dis
Main Authors: Komatsu, Haruki, Inui, Ayano, Suzuki, Yasuto, Sugiyama, Masaya, Fujisawa, Tomoo
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873716/
https://ncbi.nlm.nih.gov/pubmed/31752732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-019-4624-9
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