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Cytotoxic activity of crude extracts from Datura stramonium’s fungal endophytes against A549 lung carcinoma and UMG87 glioblastoma cell lines and LC-QTOF-MS/MS based metabolite profiling

BACKGROUND: Endophytic fungi are a proven source of bioactive secondary metabolites that may provide lead compounds for novel drug discovery. In this study, crude extracts from fungal endophytes isolated from Datura stramonium were evaluated for cytotoxic activity on two human cancer cell lines. MET...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Tapfuma, Kudzanai Ian, Uche-Okereafor, Nkemdinma, Sebola, Tendani Edith, Hussan, Raeesa, Mekuto, Lukhanyo, Makatini, Maya Mellisa, Green, Ezekiel, Mavumengwana, Vuyo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873518/
https://ncbi.nlm.nih.gov/pubmed/31752824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2752-9
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