Platelet Acetyl-CoA Carboxylase Phosphorylation: A Risk Stratification Marker That Reveals Platelet-Lipid Interplay in Coronary Artery Disease Patients

Adenosine monophosphate–activated protein kinase (AMPK) acetyl-CoA carboxylase (ACC) signaling is activated in platelets by atherogenic lipids, particularly by oxidized low-density lipoproteins, through a CD36-dependent pathway. More interestingly, increased platelet AMPK–induced ACC phosphorylation...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Kautbally, Shakeel, Lepropre, Sophie, Onselaer, Marie-Blanche, Le Rigoleur, Astrid, Ginion, Audrey, De Meester de Ravenstein, Christophe, Ambroise, Jerome, Boudjeltia, Karim Z., Octave, Marie, Wéra, Odile, Hego, Alexandre, Pincemail, Joël, Cheramy-Bien, Jean-Paul, Huby, Thierry, Giera, Martin, Gerber, Bernhard, Pouleur, Anne-Catherine, Guigas, Bruno, Vanoverschelde, Jean-Louis, Kefer, Joelle, Bertrand, Luc, Oury, Cécile, Horman, Sandrine, Beauloye, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872775/
https://ncbi.nlm.nih.gov/pubmed/31768476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.04.005
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