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Targeted delivery of lysosomal enzymes to the endocytic compartment in human cells using engineered extracellular vesicles
Targeted delivery of lysosomal enzymes to the endocytic compartment of human cells represents a transformative technology for treating a large family of lysosomal storage diseases (LSDs). Gaucher disease is one of the most common types of LSDs caused by mutations to the lysosomal β-glucocerebrosidas...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6872767/ https://ncbi.nlm.nih.gov/pubmed/31754156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53844-5 |
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